The world's bravest mice, Bernard and Miss Bianca, answer a call for help from deep in the heart of Australia's vast and unpredictable outback! With a crazy crew of local critters, these top mouse agents rush to the aid of Cody, a young boy struggling to save a magnificent eagle from a ruthless poacher. Meanwhile, Bernard is getting jealous of Jake, a kangaroo mouse who takes quite a liking to Bianca.